Immunodiagnostics · October 2025
Immunodiagnostics
Immunodiagnostic assays depend on the reliable attachment of antibodies, antigens and other biomolecules to a surface. Conventional passive adsorption can produce variable surface coverage and biomolecule orientation, potentially affecting assay sensitivity, consistency and reproducibility. This Knowledge Paper explores how Culturon’s plasma-activated coating technology enables stable covalent biomolecule immobilisation and greater control over the surface chemistry used in diagnostic and immunoassay workflows.
Why surface chemistry matters in immunodiagnostics
Immunodiagnostic assays rely on the effective immobilisation of antibodies, antigens and other biomolecules onto assay surfaces.
Passive adsorption can result in variable surface coverage, orientation and stability of immobilised biomolecules.
Culturon’s plasma-activated coatings enable stable covalent attachment rather than relying solely on physical adsorption.
Greater control over biomolecule immobilisation can support assay sensitivity, consistency and reproducibility.
Engineered surface chemistry provides a platform for developing more reliable diagnostic and immunoassay workflows.
The Immunodiagnostics Knowledge Paper explores how controlling the interaction between biomolecules and assay surfaces can improve the reliability and performance of life science diagnostics.
