Cell Culture · May 2026
Cell Culture Surfaces
Conventional cell culture plastics such as polystyrene, polypropylene and polycarbonate are widely used because they are inexpensive and easy to manufacture. However, their hydrophobicity, negative charge and chemically passive surfaces can create barriers to stable biomolecule immobilisation and reproducible cell culture. This Knowledge Paper explores how Culturon’s plasma-activated coatings modify these surface properties to enable stable covalent attachment of proteins and other biomolecules and provide greater control over cell culture surfaces.
Engineering surfaces for cell culture
Conventional cell culture plastics can present challenges including hydrophobicity, negative surface charge and limited chemical reactivity.
Culturon’s plasma-activated coatings improve surface wettability and enable stable covalent attachment of proteins, peptides, glycans, nucleic acids and other biomolecules.
Surface chemistry can be engineered to support specific cell types, biomolecules and experimental requirements.
Applications include stem cell differentiation, cancer cell culture, cell culture inserts, multi-electrode arrays and 3D culture.
Improved wettability can reduce the volume of liquid required for surface coverage, potentially reducing reagent use while improving consistency and reproducibility.
The Cell Culture Surfaces Knowledge Paper explores how engineered surface chemistry can provide greater control over the biological interface and support more reliable cell culture workflows.
